Use of Probe-based Confocal Laser Endomicroscopy to Perform Optical Biopsy for Peritoneal Nodules in Colorectal Cancer Patients During Surgery
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
During surgery, peritoneal metastasis is typically confirmed pathologically through resection sample. However, this process can be time-consuming when utilizing intro-operative frozen section pathology. To address this issue, we propose utilizing confocal laser endomicroscopy to provide in situ, real-time, and in-vivo diagnosis of suspected peritoneal nodules as cancer metastasis during surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:
• Age from over 18 to under 85 years
• American Society of Anesthesiology (ASA) score class I,II,or III
• Colorectal cancer
• Patients who be about to undergo surgical treatment
• Written informed consent
Locations
Other Locations
China
Nanfang Hospital, Southern Medical University
RECRUITING
Guangzhou
Contact Information
Primary
Jun Yan, M.D., Ph.D.
yanjunfudan@163.com
086-13825066546
Time Frame
Start Date: 2022-09-15
Estimated Completion Date: 2027-12-15
Participants
Target number of participants: 278
Treatments
Experimental: Probe-based confocal laser endomicroscopy biopsy
In this study , pCLE-based optical biopsy will be successively performed for peritoneal nodules in colorectal cancer patients during surgical operation.
Related Therapeutic Areas
Sponsors
Leads: Nanfang Hospital, Southern Medical University